AIM1. DISCOVERY OF MECHANISMS AND TREATMENTS THAT PROTECT MITOCHONDRIA FROM COPPER TOXICITY Sub-aim 1A. Screening for sub-population of mitochondria with particular sensitivity to Cu toxicity. Sub-aim 1B. Identification and validation of molecular targets that increase resistance of mitochondria to Cu in WD. Sub-aim 1C. Validation of mitochondria-specific drugs that induce tolerance to Cu overload in...Read More
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