Novel encapsulation approaches to create alternative delivery options for nutraceuticals are emerging as a promising strategy to enhance the bioavailability of poorly absorbed active food ingredients. In this context, nanoTOM aims to exploit edible plant derived nanovesicles and use them as vehicles for the encapsulation, protection, release and bioavailability enhancement of selected nutraceuticals. Plant cells...
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Extracellular vesicles (EVs) are the universal shuttles of intercellular communication, transferring lipids, proteins and nucleic acids, mediating physiological processes and spreading various diseases, including cancer and infections. The main goal of the EU-funded BOW project is to explore and develop the technology capable of lending the biological surface precision, circulation and targeting abilities of EVs...
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Here, we propose a network-biology based approach to detect and test SMN-independent treatment options. The approval of Spinraza has been a milestone for the treatment of SMA the last years. However, still there are a number of non-responders and many patients have been symptomatic for years. This is a significant problem since a delayed intervention...
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Extracellular vesicles (EVs) are cell-derived, membranous particles that mediate intercellular communication by transferring biomolecules such as proteins and RNAs. The discovery of EVs as natural biocarriers and inter-species communication means has raised great interest in the drug delivery field. EVs intrinsically possess many attributes of a drug delivery vehicle, since these particles are well tolerated...
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Truffles are esteemed edible fungi and one of the most valuable non-wood forest products that grow in symbiotic association with their host trees. They are of high economic and social value and their cultivation is of significant interest in the development of rural areas in European countries, but increasingly also in other continents. However, it...
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Apomixis, or asexual seed formation, is an alternative way to sexual reproduction that some plants use to produce viable seeds containing genetic clones of the female parent. Although it is regarded as a promising tool for breeders and farmers, apomixis does not occur in most food crops. Redirecting sexually reproducing species toward apomixis is awaited...
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Tomato is a main EU agricultural commodity, cultivated all over Europe in open and protected field and in glasshouses, representing a biological and agronomical model crop. Combined water and nutrient stress is a major problem for tomato farmers and solutions are needed to safeguard yields, while preserving the environment. TOMRES will select, among over 10,000...
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The goal of B4EST is to increase forest survival, health, resilience and productivity under climate change and natural disturbances, while maintaining genetic diversity and key ecological functions, and fostering a competitive EU bio-based economy. B4EST will provide forest tree breeders, forest managers and owners, and policy makers with: 1) better scientific knowledge on adaptation profiles...
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The goal of GenTree is to provide the European forestry sector with better knowledge, methods and tools for optimising the management and sustainable use of forest genetic resources (FGR) in Europe in the context of climate change and continuously evolving demands for forest products and services. To reach its goal, GenTree will make scientific, technological...
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