PROMPT proposes to develop a new class of porphyrinoids which pool a specific functionality for targeting mitochondria in cancer cells with high one- and two-photon photoinduced cytotoxic activity for effective PDT treatment.In case of a limited mitochondria accumulation for some of the prepared porphyrinoids, unilamellar liposomesformulated with different ratios of a cationic TPP-Bolalipid and natural...
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Extracellular vesicles (EVs) are cell-derived, membranous particles that mediate intercellular communication by transferring biomolecules such as proteins and RNAs. The discovery of EVs as natural biocarriers and inter-species communication means has raised great interest in the drug delivery field. EVs intrinsically possess many attributes of a drug delivery vehicle, since these particles are well tolerated...
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SAFE STRIP aims to introduce a disruptive technology that will achieve to embed C-ITS applications in existing road infrastructure, including novel I2V and V2I, as well as VMS/VSL functions into low-cost, integrated strips markers on the road; to make roads self-explanatory and forgiving for all road users (trucks, cars and vulnerable road users, such as...
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Next generation sequencing (NGS) technology has proved to be pivotal for elucidating the complexity and the role of the microbiome associated with plant and animals. The role of the virome as a sub-component of the microbiome is beginning to be unveiled because of new ways to analyse the data and in recognition of its importance...
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Pervasive and on-line water quality monitoring data is critical for detecting environmental pollution. However, its not easy to gather such data, at least not for all contaminants. Currently, water utilities rely heavily on frequent sampling and laboratory analysis in order to acquire this information. For this situation to be improved, portable and high-performance devices for...
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XF-ACTORS aims to establish a multidisciplinary research program to answer the urgent need to improve prevention, early detection and control of Xylella fastidiosa (Xf). Recently, Xf was introduced into Italy, where it is causing severe damage to olive crops, and in France, where so far it is limited to ornamental plants and some landscape trees....
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The objective of the GoJelly project is to develop, test and promote a gelatinous solution to microplastic pollution by developing a TRL 5-6 prototype microplastics filter (GoJelly) for commercial and public use, where the main raw material is jellyfish mucus. In doing so, the consortium addresses two environmental issues with one approach by removing the...
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Novel encapsulation approaches to create alternative delivery options for nutraceuticals are emerging as a promising strategy to enhance the bioavailability of poorly absorbed active food ingredients. In this context, nanoTOM aims to exploit edible plant derived nanovesicles and use them as vehicles for the encapsulation, protection, release and bioavailability enhancement of selected nutraceuticals. Plant cells...
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The goal of Olive-Net project is to introduce a novel approach for the exploration, valorization and marketing of new products based on bioactive compounds from Olea europaea. This will be achieved through an extended and well-balanced scheme of researcher?s secondments between universities and enterprises from EU & Associated countries as well as universities from Third...
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PROTEIN2FOODs aim is to develop innovative, cost-effective and resource-efficient plant proteins rich food sources with positive impact on human health, the environment and biodiversity. The quality and quantity of protein from selected highly nutritious seed crops (quinoa, amaranth and buckwheat), and legumes with high protein quantity (lupin, faba beans, pea, chickpea, lentil) will be significantly...
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