Colorectal cancer (CRC) is strongly affected by diet, with red and processed meat increasing risk. To understand the role of microbiome in this phenomenon and to identify specific microbiome/metabolomics profiles associated with CRC risk, we will study: 1) healthy volunteers fed for 3 months with: a high-CRC risk diet (meat-based MBD), a normalized CRC risk...
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The Knowledge Platform (KP) provides the unique possibility to connect all funded JPI HDHL researchers with other existing initiatives and relevant stakeholders in the human microbiome, nutrition and health research area. The KP will be implemented under the umbrella of the JPI HDHL ERA-Net Cofund HDHL-INTIMIC. HDHL-INTIMIC aims at coordinating national and regional research programmes...
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Nel corso di 30 mesi, il progetto creer Living Labs per la filiera del latte, nelle aree delle biotecnologie e delle TIC. I Living Labs, destinati principalmente a giovani e donne, sosterranno la creazione di nuove aziende e attivit economiche attraverso l’adozione di tecnologie emergenti applicate alla filiera del latte dal livello aziendale fino alla...
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ANADIA Niger has the aim to contribute to the development of sustainable agriculture, through the adaptation of production systems to climate change, to render them less vulnerable to extreme events, in order to support food security. To achieve this objective is necessary to strengthen the capacities of the different actors at the national and local...
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Next generation sequencing (NGS) technology has proved to be pivotal for elucidating the complexity and the role of the microbiome associated with plant and animals. The role of the virome as a sub-component of the microbiome is beginning to be unveiled because of new ways to analyse the data and in recognition of its importance...
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XF-ACTORS aims to establish a multidisciplinary research program to answer the urgent need to improve prevention, early detection and control of Xylella fastidiosa (Xf). Recently, Xf was introduced into Italy, where it is causing severe damage to olive crops, and in France, where so far it is limited to ornamental plants and some landscape trees....
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The objective of the GoJelly project is to develop, test and promote a gelatinous solution to microplastic pollution by developing a TRL 5-6 prototype microplastics filter (GoJelly) for commercial and public use, where the main raw material is jellyfish mucus. In doing so, the consortium addresses two environmental issues with one approach by removing the...
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Molecular diagnostics is still primarily a lab-based method. Emerging technologies for application at the point of care (POC) or need, i.e., where a patient or a sample is, have started gaining a big part of the molecular diagnostics market. Interestingly, available methods are divided in two groups: sophisticated instruments for ultra-sensitive temperature-regulated enzymatic amplification of...
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PROMPT proposes to develop a new class of porphyrinoids which pool a specific functionality for targeting mitochondria in cancer cells with high one- and two-photon photoinduced cytotoxic activity for effective PDT treatment.In case of a limited mitochondria accumulation for some of the prepared porphyrinoids, unilamellar liposomesformulated with different ratios of a cationic TPP-Bolalipid and natural...
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Olive oil production is of strategic importance for most economies around the Mediterranean. One of the main pests threatening olive cultivation is the olive fly. Related insects as the Mediterranean fruit fly and the invasive fly Drosophila suzukii are mayor problems in fruti- and viticulture. Given increasing limitations to the use of chemical insecticides, innovative...
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